Anti c-Myc Clone 9E11 Profile

Antigen: Myc (c)
Clone: 9E11
Subclass IgG2a
Species Raised In:

Balb/c

Immunogen: Residues 408-420. AEEQKLISEEDL.
Cross Reactivity:

Human

Applications: Frozen, Immunoprecipitation, Paraffin embedded
Growth Conditions:

DMEM + 5% FCS

Fusion Partner: Sp2
Relevance: The c-Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. c-Myc is expressed in proliferating tissues and increased c-Myc expression is found in many cancers. N-Myc is amplified in a proportion of neuroblastoma patients.
References:

Halme A et al. 2004. Cell. 116(3):405-15. PMID: 15016375 Read more
Kari B et al. 1986. J. Virol. 60:345-352. PMID: 3021969 Read more