Anti DNGR-1 Clone 397 Profile

Antigen: Mouse DNGR-1
Clone: 397
Subclass IgG21
Species Raised In:

Rat

Immunogen: RBL-2H3 cells expressing mouse DNGR-1 fused to an HA epitope.
Positive Control:

Rat IgG2a isotype-matched control mAbs.

Cross Reactivity:

Mouse

Applications: Western
Growth Conditions:

RPMI + 10% FCS + Pen + Strep + Glutamine + 2-ME

Fusion Partner: Y3 Ag 1.2.3
Synonyms: CLEC9A (C-Type lectin receptor 9A)
Relevance: Recognises mouse DNGR-1, also known as CLEC9A, which is a highly specific marker of the CD8a+ and the CD103+ DC subsets, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.