| Antigen: | p53 (N terminus) |
| Clone: | DO-7 |
| Subclass | IgG2b |
| Species Raised In: | Mouse |
| Positive Control: | MDA-MB-231 cell line |
| Cross Reactivity: | Human |
| Applications: | ELISA |
| Growth Conditions: | DMEM + 5% FCS |
| Relevance: | p53 is a stress-regulated transcription factor that regulates cell cycle arrest and was first identified as an SV40 large T antigen-binding protein. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas. |
| References: | Vojtesek B et al. 1992. J. Immunol. Methods. 151(1-2): 237-44. PMID: 1378473Read more |
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