C-Raf KI D486A Cell Line

Relevance: A MEF from the knockin of oncogenic Raf-1 D486A; in vivo study of oncogenic Raf-1 mutant and Ras signalling.
Description:

MEF produced from the Raf-1 D486A oncogenic mutant knockin mouse.

Model Type: Mouse Embryonic Fibroblast
Species/Origin:

Mouse Embryonic Fibroblast

Phenotype Keywords:
Disease Keywords:
Recommended Growth Conditions:

DMEM, 10% FCS, 100U/mol penicillin/streptomycin

References:

Noble et al. 2008. Mol Cell. 31:862-72. PMID: 18922468Read more

Notes:

See the Raf-1 D486A oncogenic mutant knockin mouse that these cells are produced from. There are also MEF lines from our other Raf mice: C-Raf KO and Raf-1FF/FF.